These conclusions were made due to the similar nature of accumulated mutations in the genome of SARS-CoV-2 and two viruses that carry bats.
During the study, the authors took as an axiom the idea that the nature of the accumulation of mutations in the genome of a particular virus will strongly depend on how the immune systems of animals or humans, which it usually affects, interact with it.
Accordingly, the similarities in how the genome of the virus changed in the recent past will show in whose organism it evolved.
The authors of the new work studied how mutations accumulate in the genomes of several dozen coronaviruses.
The evolutionary history of the origin of the coronavirus is still a mystery, since the SARS-CoV-2 genome coincides only 96% with the RNA device of its closest relative, the RaTG13 bat virus. We clarified this situation by learning about the similarity in the nature of the accumulation of mutations in the genomes of SARS-CoV-2, RaTG13 and another bats coronavirus, RshSTT182.
In this regard, the scientists stated that almost all the development of SARS-CoV-2 before the transition to the human population took place in the body of bats.