Scientists from Japan introduced a vaccine for the treatment of Alzheimer’s. This tool can be key in the prevention and treatment of degenerative cognitive states in humans.
Scientists have developed a vaccine against Alzheimer’s disease, which can dramatically change the usual methods of treatment. She was able to alter the atrophied medulla of mice by blocking the disease-causing protein. The study was published in the online version of the British scientific journal Nature.
“To use the vaccine in humans, much more research is needed, but this achievement can already help develop a cure for dementia”, said Haruhisa Inoue, a professor at Kyoto University and one of the authors of the study.
Alzheimer’s disease and other forms of dementia are characterized by abnormal accumulation of tau proteins in the brain. During the study, scientists managed to introduce the gene into a harmless virus to make it produce protein. Then they introduced the virus into mice along with genes that made them prone to dementia. The vaccine stimulated the immune system of mice, causing their bodies to create antibodies that eliminate tau proteins. Mice in which the vaccine was tested had twice as many antibodies as mice that were not given the vaccine.
In addition, only two-thirds of the brain areas of vaccinated mice were atrophied, compared to mice that were not vaccinated at all. Within 8 months of observing the mice, no side effects were recorded.
The Alzheimer’s Association estimates that more than 5 million Americans over 65 live with this disease. It is expected that by 2050 this number will triple. So far, there is no cure for Alzheimer’s disease, and some drugs help fight the symptoms, but none of them can completely cure the disease.