Scientists at the University of Manchester have discovered a new way to restore skin.
The research team, funded by the Council for Medical Research and the Helmut Horten Foundation, in a new work showed the process by which certain parts of DNA contribute to better division of human skin cells. In other words, proteins that bind DNA were able to enhance the natural process of skin cell division.
Under normal conditions, every fourth cell that emerges from the inner layer of the skin divides. However, in a new job, the team increased this figure by 20-25%. This is due to the hard-to-remove molecules that are now being used to improve the regeneration of the skin, joints and other organs.
Scientists used a sulfarafan compound found in broccoli and Brussels sprouts. Sulforaphane activates the binding of transcription factors to specific regions of DNA that control cell division and is one of a number of compounds that can work in this way.
We know that the skin sometimes cannot effectively repair itself, but an endogenous mechanism that we have discovered uses the body’s own processes to cause cell division in the skin.
Svetlana Kurinna, doctor who led the study.
One of the identified transcription factors is the main regulator of DNA in skin cells. The ultimate goal of the new work is to improve the regeneration of functional skin and possibly other organs with a similar endogenous mechanism.