The new substance alleviates the side effects of powerful antidepressants. A study by Klaus Juul Leland from the University of Copenhagen is published in the journal Nature.
Modern antidepressants are a vital tool used by a huge number of people around the world. At the same time, when a person abruptly stops taking antidepressants, withdrawal syndrome may occur, and in some patients, side effects may occur while taking the medicine in the form of a small weight gain, drowsiness, and high blood pressure.
Scientists from the University of Copenhagen have discovered a new substance called Lu AF60097, which can be added to antidepressants. With it, you can reduce the required dose of medication, as well as mitigate side effects.
“The antidepressants we use today work by contacting the same site as serotonin – on the so-called serotonin transporter (SERT). Antidepressants block the reverse transport of serotonin and, therefore, the removal of active serotonin. But such a blockage requires a relatively large dose of an antidepressant. The new drug works as an antidepressant, while not being one.”
Klaus Juul Leland