Scientists have advanced in understanding the global evolutionary process of vertebrates. In this, they were helped by a new method of genome comparison.
Comparative genomics uses genomic data to study the evolution of a species and determine the DNA sequence. This approach requires the alignment of genome sequences. This is necessary so that it is possible to compare the corresponding positions in different genomes, but the more genomes, the more difficult it is.
Researchers at the Institute of Genomics at the University of California, Santa Cruz have developed a new alignment method that allows new large-scale research. Including making the largest genome alignment for more than 600 vertebrate genomes.
Thanks to the new method, it is possible to better and more accurately understand how different species are related to each other at the genetic level.
We literally line up DNA sequences to see the corresponding positions in each genome. By its individual elements, you can see in detail what has changed and what has remained the same.
Benedict Paten, associate professor of biomolecular engineering at the University of California, Santa Cruz, and author of two new articles.
DNA sequences are conserved over millions of years of evolution, allowing scientists to pinpoint the elements of the genome that control important functions in a wide range of species.
Now scientists have to process colossal amounts of information that they will receive based on different sequences of vertebrate genomes.