A new 3D printer that rapidly produces large batches of custom biological tissues could help speed up and reduce drug development costs.
Nanoengineers at the University of California, San Diego have developed high-throughput bioprinting technology that produces 3D images at record speed. The new development can create a 96-well array of human living tissue samples in 30 minutes. This will help accelerate high-throughput preclinical drug screening and disease modeling, the researchers said.
For pharmaceutical companies, the development process for a new drug can take up to 15 years and cost $ 2.6 billion. First you need to sort through tens of thousands of tubes. Next, successful candidates are tested on animals. Eventually, with luck, one of these candidates will enter the market as an FDA-approved drug.
The high-performance 3D bioprinting technology developed at the University of California, San Diego could accelerate the first steps in this process. This will quickly create a large number of human tissues on which drugs can be tested and candidates are screened out.
Our technology allows fabrics to be created with high throughput and precision. It can really help the pharmaceutical industry quickly identify and focus on the most promising drugs.
Shaochen Chen, professor of nanoengineering at the School of Engineering, University of California, San Diego
The researchers note that while their technology cannot rule out animal testing, it can minimize disruptions that occur during this phase.