SARS-CoV-2 has a genetic trace that the natural coronavirus does not possess, according to an article by Dr. Steven Quay and Richard Mueller, a professor of physics at the University of California at Berkeley, published in The Wall Street Journal.
Experts have found a new coronavirus genome sequence in a combination of CGG-CGG. Scientists often use it to increase the contagiousness and lethality of viruses: this is a kind of signal that the insert was made in the laboratory.
In nature, CGG-CGG is extremely rare. According to Quay and Mueller, natural coronaviruses SARS or MERS do not have such a sequence. According to them, in this case, the new coronavirus simply could not get it itself.
“In fact, in the entire class of coronaviruses, which includes CoV-2, there was no CGG-CGG combination that would occur naturally. This means that the usual way viruses acquire new skills does not work in this case,” the scientists say.
Thus, proponents of zoonotic origin (that the pathogen passed to humans from an animal) should explain why SARS-CoV-2 chose the least preferred sequence during mutation and recombination-double CGG, the article says.
“Why did the virus repeat the combination that the researchers would have made in the lab? Yes, it could have happened by accident. But do you believe it?” Quay and Muller ask.
Another proof of the artificial origin of the coronavirus, American scientists called a sharp difference in its genetic diversity — compared to the viruses that cause SARS and MERS syndromes. The last two were of natural origin. As they spread among humans, they began to rapidly evolve into the most contagious forms.
SARS-CoV-2 behaved differently: it appeared in humans already adapted, in an extremely aggressive version. For several months, he did not have any serious mutations. The first such change was found in England.
According to Quay and Mueller, this case is unprecedented: it shows that the new coronavirus went through a long period of adaptation before spreading among the population. There is only one way to make a virus like this — to simulate its natural evolution and grow it on human cells until maximum efficiency is achieved. This is what laboratories that study mutations of viruses with the acquisition of functions are doing, the authors added. “The presence of the CGG sequence in CoV-2 is strong evidence of gene splicing. < … > Scientific evidence indicates that the coronavirus was developed in the laboratory,” the scientists concluded.