The passage of the $1.9 trillion fiscal package was Biden’s first legislative victory.
Earlier on Wednesday, the House held a two-hour debate ahead of the final vote.
The approval of the initiative was the first major legislative victory for President Joe Biden.
According to sources familiar with the White House plans, the president is likely to sign the bill only by the end of the week, when the last checks are completed.
Republicans believe the fiscal package is too large and not targeted enough.
Republican Marjorie Taylor Green tried to get the bill delayed, but the House of Representatives voted against such a move by 235 votes to 149.
Democrats hold 221 seats in the House of Representatives, while Republicans hold 211. During the February vote on the document, two Democrats opposed it. One of them, Kurt Schrader, said that he now intends to vote “yes,” taking into account the amendments made to the bill by the Senate.