Scientists from the United States have presented a synthetic molecule that can protect humans from coronavirus infection. This product works best as an aerosol.
A group of scientists from the University of California have developed a synthetic molecule that can be used to protect against coronavirus. They explained that the molecule is based on a tiny antibody originally found in llamas, camels, and alpacas.
Scientists named the new synthetic molecule AeroNabs and shared their results in an article published in Biorxiv and also on the Walter Lab website. According to their research, it blocks the virus’s ability to capture the ACE2 receptor, through which infection occurs. According to them, it is 200 thousand times stronger than similar antiviral drugs.
SARS-CoV-2 spreads through the spike proteins that coat its surface – it interacts with ACE2 receptors. Once the coronavirus interacts with the receptor, it can enter the cell and make it reproduce more viruses in the body.
The researchers noted that their product will work best as an aerosol – it can be used as a spray for the nose or mouth. It will provide protection against coronavirus for 24 hours. If clinical trials are successful, scientists will launch the production of AeroNabs.
In their studies, scientists tested 2 billion different synthetic nanobodies. The main criterion was the ability to prevent the spines of the coronavirus from binding to the ACE2 receptor. In the course of the research, they were able to increase their effectiveness 500 times.