An international group of researchers has found out that the drug fenofibrate and its active form fenofibric acid can destroy the SARS-CoV-2 coronavirus in human cells. This is stated in an article published in the journal Frontiers in Pharmacology.
Fenofibrate is a drug that is used to reduce cholesterol levels in patients with risks of cardiovascular diseases. Scientists have drawn attention to it in search of a drug that can disrupt the ability of the coronavirus protein spike to bind to ACE2 cellular receptors.
Laboratory experiments on cell cultures have shown that fenofibrate can reduce the viral load by 70%. At the same time, it showed the same effectiveness against most strains of SARS-CoV-2. But its effectiveness against the “delta” strain of coronavirus is still being studied.
The scientists noted that fenofibrate is very cheap and available all over the world, so it can be very useful in low-and middle-income countries and patients who are not recommended for vaccination.